Posted February 22, 2010
Revised March 3, 2010
Copyright © by YSU Center for Applied Chemical Biology

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Dr. Ganesaratnam Balendiran
Associate Professor
Department of Chemistry

  • Ph.D., 1991, The University of Wisconsin at Madison
  • B.S., 1985, University of Sri Lanka
Telephone/Voice: 330.941.7103
Facsimile: 330.941.1579

Research Interests: 

Research in the laboratory is focused on structure based function and activity studies of molecules involved in sugar metabolism, nucleotide metabolism and gene regulation. Molecules hide in them unique structural features which play important roles in their physical and biological properties.

Representative Publications:
  • Klemin S, Calvo RY, Bond S, Dingess H, Rajkumar B, Perez R, Chow L, BALENDIRAN GK. WY 14,643 inhibits human aldose reductase activity. Journal of Enzyme Inhibition and Medicinal Chemistry 21: 569-573, 2006. [PubMed Link]
  • BALENDIRAN GK, Verma M, Perry E. Chemistry of fibrates. Current Chemical Biology 3: 311-316, 2007.
  • Verma M, Martin H-J, Haq W, O'Connor TR, Maser E, BALENDIRAN GK. Inhibiting wild-type and C299S mutant AKR1B10; a homologue of aldose reductase upregulated in cancers. European Journal of Pharmacology 584: 213-221, 2008.  [PubMed Link]  [OhioLink]
  • BALENDIRAN GK, Martin H-J, El-Hawari Y, Maser E. Cancer biomarker AKR1B10 and carbonyl metabolism. Chemico-Biological Interactions 178: 134-137, 2009.
  • [PubMed Link]  [OhioLink]
  • BALENDIRAN GK. Fibrates in the chemical action of daunorubicin. CurrentCancer Drug Targets 9: 366-369, 2009.
  • [PubMed Link]

CACB Principle Investigators
[links to research project descriptions and contact information for each PI]
  >  Dr. David Asch
  >  Dr. Ganesaratnam Balendiran
  >  Dr. Jon Caguiat
  >  Dr. Chet Cooper
  >  Dr. Diana Fagan
  >  Dr. Jozsi Jalics
  >  Dr. Xiangjia Min
  >  Dr. Peter Norris
  >  Dr. Yogen Panta
  >  Dr. Doug Price
  >  Dr. Nina Stourman
  >  Dr. Gary Walker
  >  Mr. Rob Wardle
  >  Dr. George Yates

Other CACB Personnel
  >  Staff    
 Graduate Students
  >  Undergraduate Students
  >  Alumni


The CACB in Detail
   > Center Concept
> Scope of Activities
> Technological Capabilities
Sponsored Research Projects
> Faculty Research Groups
> Collaborators
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