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"Welcome to Medical
Mycology"
I am Dr. Chet
Cooper, your course instructor for BIOL 4849, Medical Mycology. BIOL 4849 is three
semester-hour upper-division course at Youngstown State University
(YSU)
intended for undergraduate students majoring in biology, but students
in other majors may also find this course quite beneficial.
As your instructor, I am wholly
committed to providing
you a sound education in the foundations of fungal diseases, which are
also known by the scientific term "mycoses". With
the same commitment on your part, I guarantee that your experiences in
this course will give you a different and accurate perspective of the
role that fungi play in causing disease in humans and animals.
I very much look forward to an exceptional enjoyable semester as
your instructor. Should you have any questions or
comments about anything related to this, please be sure to
contact me.
Best Wishes for a Great Semester in Medical Mycology!
Course Description:
(as
published on page 263 of the 2007-2008 YSU Undergraduate Bulletin)
BIOL 4849. Medical Mycology.
Survey of infectious diseases caused by fungi including their etiology,
epidemiology, histopathology, diagnosis, and treatment.
Host-parasite interactions and the environmental and molecular factors
that contribute to establishment of fungal disease in humans and
animals. Prereq.: BIOL 3702. 3 s.h.
Note:
Students wishing to take this course but who do not hold the
pre-requisite course, Microbiology (BIOL 3702), should see Dr. Cooper
regarding possible solutions.
Course Goals and Objectives:
The goal of BIOL 4849 is to prepare students for
professional careers that employ the principles of medical
mycology. This will be accomplished through the mastery of the
following specific objectives:
- Discover
how other disciplines contributed to the study of mycotic diseases;
- Recognize
the etiology of different mycoses;
- Learn
the fundamental basis for diagnosing fungal infections;
- Differentiate
the different pathologies of the mycoses;
- Identify
environmental and host factors that promote fungal infections;
- Comprehend
the various treatment regimens for the mycoses;
- Appreciate
the role of fungi in human affairs;
- Recognize
the importance of proper public dissemination of information; and
- Understand
the contributions of fungi to current concepts in infectious disease
Course Materials:
There is no standard textbook for this course. However, most of
Dr. Cooper's lecture material will come from a variety of sources
including the following:
- Atlas of Fungal Infections, 2nd ed.
2007. Carol A. Kauffman, ed. Springer.
Located in the Maag Library Reserves (ask
at the Circulation Desk, Main Floor) under the following call number:
RC117
.A86 2007 [textbook]
RC117 .A86 2006x CD-ROM [CD-ROM
version of textbook]
- Clinical Mycology.
2003. Elias J. Anaissie, Michael R. McGinnis, Michael A. Pfaller,
eds. Churchill Livingstone.
Located in the Maag Library Reserves (ask
at the Circulation Desk, Main Floor) under the following call number: QR245 .C565 2003
- Clinical Mycology.
2003. William E. Dismukes, Peter G. Pappas, Jack D. Sobel,
eds. Oxford University Press.
Located in the Maag Library Reserves (ask
at the Circulation Desk, Main Floor) under the following call number: QR245
.C566 2003
- Topley & Wilson's Microbiology &
Microbial Infections, 10th ed. 2005. Vol. 3.
Medical Mycology. Hodder Arnold.
Located in the Maag Library Reserves (ask
at the Circulation Desk, Main Floor) under the following call number: QR46 .T6 2005x [be sure to request volume 3 of this
series]
- Medical Mycology. 1992. K.J.
Kwon-Chung and John E. Bennett. Lea & Febiger.
Maag
Library does not own this book. However, limited numbers of this
book available via OhioLink (interlibrary
loan) by clicking here.
In addition, the following items have been placed on reserve in the
Maag Library (3-hour in-library use):
- Identifying Filamentous Fungi. A Clinical
Laboratory Handbook. 1996. St-Germain, G. and Summerbell, R.
Star Publishing.
- Pathologic Diagnosis of Fungal Infections.
1987. Chandler, F. W. and Watts, J. C. ASCP Press.
- Medical Mycology and Human Mycoses.
1996. Beneke, E. S. and Rogers, A. L. Star Publishing.
- Medically Important Fungi: A Guide to
Identification. 1995. Larone, D. H. ASM Press.
- Medical Mycology: A Self-Instructional Text.
1997. Kern, M. E. and Blevins, K. S.
- Medical Mycology: A Practical Approach.
1989. Evans, E. G. V. and Richardson, M. D. IRL Press.
- Color Atlas of Pathogenic Fungi.
1979. Frey, D., Oldfield, R. J., and Bridger, R. C. Year
Book Medical Publishers.
Please
note that some of the above books are the personal property of Dr.
Cooper. As with any library book, please handle them with great
care and respect.
In lieu of a textbook and in addition to the above reserve materials,
students are encouraged to refer to qualified web resources. Use
caution! There are a number of web sites that discuss fungi and
the infections they cause. Listed below are some excellent web
sites endorsed for use in this course:
Other
web site links may be added in the near future, so check back
periodically.
Finally, Dr. Cooper and your peers will make available a number of
electronic versions of journal articles for you to read. These
will be available for downloading directly from this web page or from
the Electronic Journal
Center of OhioLink.
Grade Components:
A
student's final grade in BIOL
4849 will be based upon
scores earned in three lecture examinations and two group
presentations. Each
examination is worth 100 points, whereas each presentation is worth
75
points, of which students will make two. Attendance will be
taken, beginning on the third day of
the course, and will be worth 50 points towards a student's final
grade. For a student to receive a full day's attendance points,
he/she must be present for the entire period. Hence, there are a
total of 500 points in this course.
The format of the examinations may vary to include short
essay,
multiple-choice, true-false, and matching questions.
Students who are absent from an examination will have a score of "0"
recorded. No exemptions to taking the examination on the
scheduled
date will be given except in cases of extreme circumstances. The
decision of whether or not to grant an exemption is entirely at the
discretion of the instructor and is not subject to further appeal.
Student presentations will be small group projects and will be both
peer and instructor graded according
to a rubric that will be described prior to the assignment of topics.
No
opportunities will be granted for earning extra credit. Student
initiated requests for extra credit opportunities
will not be entertained and may be acidly received.
Grading Scale.
The following scale will be used to assign final grades for this course:
| Final Grade |
Total
Points |
| A (90% or greater) |
450 points or more |
| B (80 to 89 %) |
400 to 449 points |
| C (70 to 79%) |
350 to 399 points |
| D (60 to 69%) |
300 to 349 points |
| F (59% or less) |
299 points or less |
This grading scale is absolute. This is no "curving" of grades.
Resources
Used By
The Course Instructor:
Unless otherwise noted by Dr.
Cooper,
all material presented to students in this course represents either i)
selected portions of information contained within the noted textbook(s)
or supplementary material, ii) information published in the scientific
literature, iii) current issues reported by the news media, or iv)
knowledge otherwise commonly known to professional
microbiologists or mycologists. Dr. Cooper makes no claim of
"ownership"
of facts and/or ideas presented in this
course unless
specifically noted. All facts and/or ideas are used solely for
educational purposes. Dr. Cooper makes every effort to
appropriately attribute facts and/or
ideas to their proper sources.
Academic
Dishonesty:
Academic
dishonesty, in any form, will not be tolerated in this course.
Students
are urged to read the
section on “Academic
Honesty" as printed
on page 40 of the YSU Undergraduate
Bulletin, 2005-2006.
Students should also be aware of pertinent sections in The Code (the latter
is a PDF document).
Any student enrolled in BIOL
4849
shown to have committed academic
dishonesty in this course is deemed solely accountable for his/her
actions and will receive a final course grade of "F".
Additional sanctions may also be sought, i.e., a recommendation by the
instructor for dismissal of the student from the University.
Be aware that this policy includes unauthorized access of computer
files associated with this course. The web site files associated
with BIOL 4849 are monitored for unauthorized access.
Entering
these files even by "accident"
will be considered a
violation of
academic integrity.
Disability
Statement:
In accordance with
University procedures, students who have a documented disability and
require accommodations to obtain equal acess in this course must
contact Dr. Cooper privately
to discuss the individual's specific
needs. Persons enrolled in this course and currently having a
documented disability must notify Dr. Cooper of their needs no later
than May 29, 2008. In addition, students having a disability
must be properly registered with the Disability
Services Office (Beeghly Hall, Room 3310; telephone
330.941.1372). Also, to be properly
registered, a letter of
accommodations verifying the student's eligibilty must be
provided. Individuals who develop a disability during the
semester must notify Dr. Cooper within one week after being properly
registered with the Disability Services
Office. Students with disabilities are reminded that in addition
to certain rights and privileges covered by law and University policy,
they also have obligations and responsibilities that must be met.
Students are strongly encouraged to review these rights and
responsibilities as outlined on the Disability
Services Office
web page.
Other
Responsibilities/Expected Behavior:
Electronic
Communication/Data
Storage Devices. During lecture, all
cellular telephones,
pagers, or other electronic communication devices must be turned off or
set in the quiet/vibration mode of operation. Data storage
devices (e.g., personal desk assistants, lap top computers, etc.) may
be used during lectures and only if they do not cause distraction to
other students or the course instructor. Students failing to meet
this expectation will be invited to leave the classroom until such time
that they comply with this policy.
During examinations and
quizzes, all electronic devices (including personal desktop
assistants, computers, etc.) are strictly prohibited.
Students violating this policy will be suspected to have committed
academic dishonesty.
Recording
of Lectures.
Students are reminded that Dr.
Cooper's lectures are copyright
protected (see Copyright
Restrictions).
However, students are permitted to electronically record
lectures in the classroom provided that: i) such activity is not
disruptive to the instructor or fellow students; ii) the recording is
used solely for the personal study of the student making the recording;
iii) the recording is not sold or transmitted to others in any form
without the expressed written permission of Dr. Cooper; and iv) the
recording does not serve as a substitute for attending class or
actively participating in the lecture.
Examinations. Examinations
are to be
taken without assistance from other students. If you are aware of
any student cheating or having a copy of the current exam, please
contact the instructor. Academic dishonesty in any form will not
be tolerated in this course. Penalties for such action will be
enforced.
Decorum.
At all times,
students are expected to exhibit behavior appropriate for young (or
even older) adults. Such behavior is delimited by University
policy. Inappropriate behavior, including disrespect for Dr.
Cooper, is subject to expulsion from one or more lecture sessions
without the opportunity to begin or complete the assigned
exercises. In cases of extremely inappropriate behavior, Dr.
Cooper will recommend more severe sanctions (including dismissal from
the University).
[Back
To Top of Page]
Moldt phase of Penicillium
marneffei. Lactophenol cotton blue
stain from a slide culture (C. R. Cooper, Jr.)
Posting of Grades/Scores:
Student
grades/scores are periodically posted via this web page. However,
students must provide their approval to have their individual
grades/scores posted via the downloadable Grade
Posting Permission Form. [click on the button below to
download this form]
Wtihout this form,
individual student scores/grades will not be posted. A student
may withdraw this permission at anytime by written notice to the course
instructor.
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[FINAL
GRADES: Posted
on June 28, 2008]
[required
by May 29th]
[required
for posting of your scores/grades]
Course Calendar
Tuesday,
May 20th
Course
Introduction
What are Fungi?
Lecture
Outline (PDF)
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Thursday,
May 22nd
Today's
class will begin at 8:00 AM, not 7:30 AM.
Students
are to report directly to the
Library Database Presentation, Maag
Library
8:00 AM, 4th Floor Instruction
Laboratory
[includes a 5 bonus point exercise (to be
announced)]
[After this
session, form your presentation group and provide the names of the team
members to Dr. Cooper and your team name (see choices below).
Next, choose a topic, get approval from Dr. Cooper who will be in the
library on the 4th floor near the Tech Desk unitl about 9:45 AM]
Presentation
Teams and Their Members:
Team
Candidiasis - Neel Parekh, Michael Dinh, Aditi
Gupta,
Nick Rose
Team Penicillia - Kyren Gardner, Anubhav Vinayak,
Heather
Team Dematiaceae - A.J. Cook, Caitlin Merrin, Jim Antil
Team Loboa - Meghan Fossett, Andrew Brown, Vince
Florio
**************************************
What are Fungi?
(cont., 10:00 AM - 10:50 AM)
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Tuesday,
May 27th
Today's
class will begin at 8:45 AM, not 7:30 AM. Use this time to get
together with your group and perhaps use the library resources to begin
researching your presentation topic. Maag Library opens at 7:30
AM. You can also use the lecture hall (Room 3022) to meet with
your group. Dr. Cooper will be in his office (Room 4015) should
you need help.
Epidemiology
and Laboratory
Aspects of Fungal
Infections
Lecture
Outline
(PDF)
Histopathology
of
Fungal
Infections
Lecture
Outline
(PDF)
Antifungal
Agents and
Antifungal Therapy
Lecture
Outline (PDF)
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Thursday,
May 29th
Due
to unforeseen circumstances, class will not formally meet today.
Use this time to get
together with your group and perhaps use the library resources to begin
researching your presentation topic. Maag Library opens at 7:30
AM. You
can also use the lecture hall (Room 3022) to meet with your
group. Dr.
Cooper will be in his office (Room 4015) from 7:30 AM to 8:45 AM and
from 10:30 AM to 11:30 AM should you need help.
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Tuesday,
June 3rd
Exam
I (7:30 AM - 8:45 AM)
Superficial Fungal Infections (Dr. Cooper)
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Thursday,
June 5th
Library Research of Student
Topics/Case Reports
Maag Library
[Note:
Dr. Cooper will be available to assist students from 8:00 AM to 10:00
AM. He will be located on the 4th floor of the library somewhere
near the Tech Desk area].
Presentation
Template (click on link below)
Medical
Mycology Presentation Template
(PowerPoint File)
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Tuesday,
June 10th
Class will begin
at 8:00 AM today
(Use the
time from 7:30 AM until 8:00 AM to work together in your presentation
groups)
Student
Presentation 1: Dermatomycoses
(presented by
Team Loboa)
Lecture
Outline (.doc)
Case
Report 1 (PDF)
Case
Report 2 (PDF)
Case
Report 3 (PDF)
Student
Presentation 2: Sporotrichosis
(presented by Team Dematiaceae)
Lecture
Outline (.doc)
Case
Report 1 (OhioLink)
Case
Report 2 (OhioLink)
Case
Report 3 (OhioLink)
A critical review of the above
presentations will take place and followed with time devoted to group
work on future presentations
Student
Presentation 3: Zygomycosis
(presented by
?)
Lecture
Outline (PDF)
Case
Report 1 (PDF)
Case
Report 2 (PDF)
Case
Report 3 (PDF)
Student
Presentation 4: Eumycetoma
(presented by
?)
Lecture
Outline (PDF)
Case
Report 1 (PDF)
Case
Report 2 (PDF)
Case
Report 3 (PDF)
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Thursday,
June 12th
Class will begin
at 8:00 AM today
(Use the
time from 7:30 AM until 8:00 AM to work together in your presentation
groups)
Student
Presentation 5: Candidiasis
(presented by Team Candidiasis)
Lecture
Outline (.doc)
Case
Report 1 (PDF)
Case
Report 2 (PDF)
Case
Report 3 (PDF)
Special
Webinar Presentation [CLICK
HERE]
Student
Presentation 6: Cryptococcosis
(presented by
?)
Lecture
Outline (PDF)
Case
Report 1 (PDF)
Case
Report 2 (PDF)
Case
Report 3 (PDF)
Student
Presentation 7: Aspergillosis
(presented by
?)
Lecture
Outline (PDF)
Case
Report 1 (PDF)
Case
Report 2 (PDF)
Case
Report 3 (PDF)
Student
Presentation 8: Pythiosis
(presented by
?)
Lecture
Outline (PDF)
Case
Report 1 (PDF)
Case
Report 2 (PDF)
Case
Report 3 (PDF)
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Tuesday,
June 17th
Exam
II (7:30 AM - 8:45 AM)(9:00 AM - 10:55 AM)
Library Research of Student
Topics/Case Reports
Maag Library
[Note:
Dr. Cooper will be available to assist students from 9:00 AM to 10:00
AM. He will be located on the 4th floor of the library somewhere
near the Tech Desk area].
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Thursday,
June 19th
Class will begin
at 8:00 AM today
(Use the
time from 7:30 AM until 8:00 AM to work together in your presentation
groups)
Student
Presentation 9: Histoplasmosis
(presented by Team Candidiasis)
Lecture
Outline (.doc)
Case
Report 1 (PDF)
Case
Report 2 (PDF)
Case
Report 3 (PDF)
Student
Presentation 10: Blastomycosis
(presented by Team Penicillia)
Lecture
Outline (PDF)
Case
Report 1 (PDF)
Case
Report 2 (PDF)
Case
Report 3 (PDF)
Student
Presentation 11: Coccidioidomycosis
(presented by Team Loboa)
Lecture
Outline (.doc)
Case
Report 1 (web link)
Case
Report 2 (OhioLink)
Case
Report 3 (OhioLink)
Student
Presentation 12: Paracoccidioidomycosis
(presented by
?)
Lecture
Outline (PDF)
Case
Report 1 (PDF)
Case
Report 2 (PDF)
Case
Report 3 (PDF)
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Tuesday,
June 24th
Class will begin
at 8:00 AM today
Student
Presentation 13: Hyalohyphomycosis
(presented by
?)
Lecture
Outline (PDF)
Case
Report 1 (PDF)
Case
Report 2 (PDF)
Case
Report 3 (PDF)
Student
Presentation 14:Chromoblastomycosis
(presented by Team Dematiaceae)
Lecture
Outline (.doc)
Case
Report 1 (OhioLInk)
Case
Report 2 (OhioLInk)
Case
Report 3 (OhioLInk)
Student
Presentation 15: Phaeohyphomycosis
(presented by
?)
Lecture
Outline (PDF)
Case
Report 1 (PDF)
Case
Report 2 (PDF)
Case
Report 3 (PDF)
Student
Presentation 16: Lobomycosis
(presented by Team Penicillia)
Lecture
Outline (.doc)
Case
Report 1 (PDF)
Case
Report 2 (PDF)
Case
Report 3 (PDF)
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Thursday,
June 26th
Exam
III
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Multiple skin lesions due to disseminated infection
of Coccidioides immitis
(courtesy of www.doctorfungus.org)
Attendance:
A record of attendance
will be
kept
beginning on the third day of the course. Attendance is
worth 50 points towards a student's final grade. Each lecture
day, except for June 5th and June26th, is worth 6 points. For
June 7th, a
library work day, attendance is worth 2 points. For a student to
receive a full day's attendance points, he/she must be present for the
entire period.
Please note, the lecture for this course
begins promptly at 7:30 AM on Tuesdays and Thursdays throughout the
semester. Also, be aware that this course operates on "Ward
Beecher Time", which may
or may not
correlate to the time that exists at other places on campus.
Students are strongly encouraged to synchronize their
timepieces as well as to arrive early enough to find a suitable parking
place.
On those dates for which an examination is scheduled, students
who are late may not be permitted to take the examination. This
is
entirely at Dr. Cooper's discretion.
Moreover, except
for extenuating circumstances,
it is generally unacceptable for a student to request to take an
examination at a time other than the scheduled date. Having a
second
examination the day before, the day after, or on the same day is
absolutely certain not to evoke any sympathy from Dr. Cooper.
Please do not even ask for special dispensation for such a
reason.
However, Dr. Cooper is willing to listen (and perhaps chuckle to
himself) other reasons that a student may deem to be extenuating
(please note - havng in excess of two grandmothers die during the
semester will be considered suspicously gratuitous). The
decision
regarding the student's reasoned argument/request for a change in the
examination date/time is solely at Dr. Cooper's discretion and, once
rendered, is final.
Required
CUE Mail Account:
All electronic
communications with students enrolled in BIOL 4849 will only be
made
using the University's CUE (Common
University Email) Mail
system. All BIOL 4849 students must establish their CUE mail
accounts if they have not done so already. To activate your free
CUE mail account, go the CUE Frequently Asked Questions section of the
web page located at the following URL: http://helpdesk.ysu.edu. Please note that a CUE mail
account does not have to supplant your
current non-CUE mail service. A feature of CUE mail is that all
incoming messages can be forwarded to another email account.
Hence, you can retain your present services and still receive all
communications from Dr. Cooper.
Distribution of
Course Material:
All original material on
the BIOL 4849 course web site, as well as all original material
presented in either the classroom or laboratory, including
orally-transmitted lectures, is considered protected by a copyright
held by Dr. Cooper. In general, students enrolled in BIOL
4849
have permission to download, print, and distribute materials
copyrighted by Dr. Cooper without his expressed written permission so
long as such materials are not used for activities i) associated with
the commission of academic dishonesty, ii) intended to circumvent
course policies, iii) which result in monetary profit by either the
student or others, and iv) that do not violate copyright
protections. For further information, please see Copyright
Restrictions.
Syllabus Acknowledgement Form:
All
students enrolled in this course must read this electronic
syllabus and verify that they have done so by
submitting a completed Syllabus
Acknowledgement Form.
[click on the button below to download this form]
No grades will be given until this form is received.
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