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"Welcome to Medical
Mycology"
I am Dr. Chet
Cooper, your course instructor for BIOL 4849, Medical Mycology. BIOL 4849 is three
semester-hour upper-division course at Youngstown State University
(YSU)
intended for undergraduate students majoring in biology, but students
in other majors may also find this course quite beneficial.
As your instructor, I am wholly
committed to providing
you a sound education in the foundations of fungal diseases, which are
also known by the scientific term "mycoses". With
the same commitment on your part, I guarantee that your experiences in
this course will give you a different and accurate perspective of the
role that fungi play in causing disease in humans and animals.
I very much look forward to an exceptional enjoyable semester as
your instructor. Should you have any questions or
comments about anything related to this, please be sure to
contact me.
Best Wishes for a Great Semester in Medical Mycology!
Course Description:
(as
published in the 2010-2011 YSU Undergraduate Bulletin)
BIOL 4849. Medical Mycology.
Survey of infectious diseases caused by fungi including their etiology,
epidemiology, histopathology, diagnosis, and treatment.
Host-parasite interactions and the environmental and molecular factors
that contribute to establishment of fungal disease in humans and
animals. Prereq.: BIOL 3702. 3 s.h.
Note:
The pre-requisite for this course has been changed to BIOL 2602.
The current description has yet to be ammended.
Course Goals and Objectives:
The goal of BIOL 4849 is to prepare students for
professional careers that employ the principles of medical
mycology. This will be accomplished through the mastery of the
following specific objectives:
- Discover
how other disciplines contributed to the study of mycotic diseases;
- Recognize
the etiology of different mycoses;
- Learn
the fundamental basis for diagnosing fungal infections;
- Differentiate
the different pathologies of the mycoses;
- Identify
environmental and host factors that promote fungal infections;
- Comprehend
the various treatment regimens for the mycoses;
- Appreciate
the role of fungi in human affairs;
- Recognize
the importance of proper public dissemination of information; and
- Understand
the contributions of fungi to current concepts in infectious disease
Course Materials:
There is no standard textbook for this course. However, the
following is a
RECOMMENDED text:
Clinical Mycology, 2nd ed.
2009. Elias J. Anaissie, Michael R. McGinnis, Michael A. Pfaller,
eds. Churchill Livingstone.
Located in the
Maag Library Reserves (ask
at the Circulation Desk, Main Floor) under the following call number: QR245 .A53 2009x
Plese note the following:
i) The
above text is NOT REQUIRED. It will help (if you read it), but if
you
have good study habits, you won't necessarily need it.
ii) I
will use material from the recommended text, but my exams will come 99%
or greater from my notes (or yours, as the case will be), as well as
the presentations you and your peers make to the class.
In
addition, much of
Dr. Cooper's lecture material will come from a variety of sources
including the following:
- Atlas of
Fungal Infections, 2nd ed.
2007. Carol A. Kauffman, ed. Springer.
Located in the
Maag Library Reserves (ask
at the Circulation Desk, Main Floor) under the following call number:
RC117
.A86 2007 [textbook]
RC117 .A86 2006x
CD-ROM [CD-ROM
version of textbook]
- Clinical Mycology.
2003. Elias J. Anaissie, Michael R. McGinnis, Michael A. Pfaller,
eds. Churchill Livingstone.
Located in the
Maag Library Reserves (ask
at the Circulation Desk, Main Floor) under the following call number: QR245 .C565 2003
- Clinical Mycology, 2nd ed.
2009. Elias J. Anaissie, Michael R. McGinnis, Michael A. Pfaller,
eds. Churchill Livingstone.
Located in the
Maag Library Reserves (ask
at the Circulation Desk, Main Floor) under the following call number: QR245 .A53 2009x
- Clinical Mycology.
2003. William E. Dismukes, Peter G. Pappas, Jack D. Sobel,
eds. Oxford University Press.
Located in the
Maag Library Reserves (ask
at the Circulation Desk, Main Floor) under the following call number: QR245
.C566 2003
- Topley & Wilson's Microbiology &
Microbial Infections, 10th ed. 2005. Vol. 3.
Medical Mycology. Hodder Arnold.
Located in the
Maag Library Reserves (ask
at the Circulation Desk, Main Floor) under the following call number: QR46 .T6 2005x [be sure to
request volume 3 of this
series]
- Medical Mycology. 1992. K.J.
Kwon-Chung and John E. Bennett. Lea & Febiger.
Maag
Library does not own this book. However, limited numbers of this
book available via OhioLink (interlibrary
loan) by clicking here.
In
addition, the following items have been placed on reserve in the
Maag Library (3-hour in-library use):
- Identifying Filamentous Fungi. A Clinical
Laboratory Handbook. 1996. St-Germain, G. and Summerbell, R.
Star Publishing.
- Pathologic Diagnosis of Fungal Infections.
1987. Chandler, F. W. and Watts, J. C. ASCP Press.
- Medical Mycology and Human Mycoses.
1996. Beneke, E. S. and Rogers, A. L. Star Publishing.
Please
note that some of the above books are the personal property of Dr.
Cooper. As with any library book, please handle them with great
care and respect.
Also, some additional electronic resources you should consider using
during this course:
- Immunology of fungal infections
[electronic resource] / edited by Gordon D. Brown and Mihai G. Netea.
Dordrecht : Springer, 2007. Persitent Link
- Diagnosis and treatment of human Mycoses
[electronic resource] / edited by Duane R. Hospenthal, Micheal G.
Rinaldi. Totowa, N.J. : Humana Press, 2008. Persistent Link
- Pathogenic yeasts [electronic
resource] / edited
by Ruth Ashbee, Elaine M. Bignell. Berlin; London :
Springer, 2010. Persistent Link
- New
insights in medical mycology [electronic resource] / edited by Kevin
Kavanagh. Dordrecht : Springer, 2007. Persistent Link
- Medical
Mycology (journal) [electronic
resource] Available on EBSCOhost. Full text available 2/1/2003 - . (Due
to publisher restrictions, the most recent 12 months are not
available.). Persistent Link
SPECIAL NOTE: If
you need an article dated 2010-2011 from this journal, contact Dr.
Cooper for assistance.
In
lieu
of a textbook and in addition to the above reserve materials,
students are encouraged to refer to qualified web resources. Use
caution! There are a number of web sites that discuss fungi and
the infections they cause. Listed below are some excellent web
sites endorsed for use in this course:
Other
web site links may be added in the near future, so check back
periodically.
Finally, Dr. Cooper and your peers may make available a number of
electronic versions of journal articles for you to read. These
will be available for downloading directly from this web page or from
the Electronic Journal
Center of OhioLink.
Grade
Components:
A
student's final grade in BIOL
4849 will be based upon
scores earned in four lecture examinations and three group
presentations. Each
examination is worth 100 points, whereas each presentation is worth 100
points, of which students will make two. Attendance will be
taken, beginning on the second day of
the course, and will be worth 150 points (5 points for each session)
towards a student's final
grade. For a student to receive a full day's attendance points,
he/she must be present for the entire period. Hence, there are a
total of 650 points in this course.
The format of the examinations may vary to include short
essay,
multiple-choice, true-false, and matching questions.
Students who are absent from an examination will have a score of "0"
recorded. No exemptions to taking the examination on the
scheduled
date will be given except in cases of extreme circumstances. The
decision of whether or not to grant an exemption is entirely at the
discretion of the instructor and is not subject to further appeal.
Student presentations will be small group projects and will be both
peer and instructor graded according
to a rubric that will be described prior to the assignment of topics.
No
opportunities will be granted for earning extra credit. Student
initiated requests for extra credit opportunities
will not be entertained and may be acidly received.
Grading Scale.
The following scale will be used to assign final grades for this course:
| Final
Grade |
Total
Points |
| A
(90% or greater) |
585
points or more |
| B
(80 to 89 %) |
520
to 584 points |
| C
(70 to 79%) |
455
to 519 points |
| D
(60 to 69%) |
390
to 454 points |
| F
(59% or less) |
389
points or less |
This grading scale is absolute. This is no "curving" of grades.
Resources
Used By
The Course Instructor:
Unless otherwise noted by Dr.
Cooper,
all material presented to students in this course represents either i)
selected portions of information contained within the noted textbook(s)
or supplementary material, ii) information published in the scientific
literature, iii) current issues reported by the news media, or iv)
knowledge otherwise commonly known to professional
microbiologists or mycologists. Dr. Cooper makes no claim of
"ownership"
of facts and/or ideas presented in this
course unless
specifically noted. All facts and/or ideas are used solely for
educational purposes. Dr. Cooper makes every effort to
appropriately attribute facts and/or
ideas to their proper sources.
Academic
Dishonesty:
Academic
dishonesty, in any form, will not be tolerated in this course.
Students
are urged to read the
section on "Academic
Honesty" as printed
in the YSU Undergraduate
Bulletin, 2010-2011.
Students should also be aware of pertinent sections in The Code (the latter
is a PDF document).
Any student enrolled in BIOL
4849
shown to have committed academic
dishonesty in this course is deemed solely accountable for his/her
actions and will receive a final course grade of "F".
Additional sanctions may also be sought, i.e., a recommendation by the
instructor for dismissal of the student from the University.
Be aware that this policy includes unauthorized access of computer
files associated with this course. The web site files associated
with BIOL 4849 are monitored for unauthorized access.
Entering
these files even by "accident"
will be considered a
violation of
academic integrity.
Disability
Statement:
In accordance with
University procedures, students who have a documented disability and
require accommodations to obtain equal acess in this course must
contact Dr. Cooper privately
to discuss the individual's specific
needs. Persons enrolled in this course and currently having a
documented disability must notify Dr. Cooper of their needs no later
than July 8, 2011. In addition, students having a disability
must be properly registered with the Disability
Services Office (275 Fifth Avenue; telephone
330.941.1372). Also, to be properly
registered, a letter of
accommodations verifying the student's eligibilty must be
provided. Individuals who develop a disability during the
semester must notify Dr. Cooper within one week after being properly
registered with the Disability Services
Office. Students with disabilities are reminded that in addition
to certain rights and privileges covered by law and University policy,
they also have obligations and responsibilities that must be met.
Students are strongly encouraged to review these rights and
responsibilities as outlined on the Disability
Services Office web page.
Other
Responsibilities/Expected Behavior:
Electronic
Communication/Data
Storage Devices. During lecture, all
cellular telephones,
pagers, or other electronic communication devices must be turned off or
set in the quiet/vibration mode of operation. Data storage
devices (e.g., personal desk assistants, lap top computers, etc.) may
be used during lectures and only if they do not cause distraction to
other students or the course instructor. Students failing to meet
this expectation will be invited to leave the classroom until such time
that they comply with this policy.
During examinations and
quizzes, all electronic devices (including personal desktop
assistants, computers, etc.) are strictly prohibited.
Students violating this policy will be suspected to have committed
academic dishonesty.
Recording
of Lectures.
Students are reminded that Dr.
Cooper's lectures are copyright
protected (see Copyright
Restrictions).
However, students are permitted to electronically record
lectures in the classroom provided that: i) such activity is not
disruptive to the instructor or fellow students; ii) the recording is
used solely for the personal study of the student making the recording;
iii) the recording is not sold or transmitted to others in any form
without the expressed written permission of Dr. Cooper; and iv) the
recording does not serve as a substitute for attending class or
actively participating in the lecture.
Examinations. Examinations
are to be
taken without assistance from other students. If you are aware of
any student cheating or having a copy of the current exam, please
contact the instructor. Academic dishonesty in any form will not
be tolerated in this course. Penalties for such action will be
enforced.
Decorum.
At all times,
students are expected to exhibit behavior appropriate for young (or
even older) adults. Such behavior is delimited by University
policy. Inappropriate behavior, including disrespect for Dr.
Cooper, is subject to expulsion from one or more lecture sessions
without the opportunity to begin or complete the assigned
exercises. In cases of extremely inappropriate behavior, Dr.
Cooper will recommend more severe sanctions (including dismissal from
the University).
[Back
To Top of Page]
Moldt phase of Penicillium
marneffei. Lactophenol cotton blue
stain from a slide culture (C. R. Cooper, Jr.)
Posting
of Grades/Scores:
Student
grades/scores are periodically posted via this web page. However,
students must provide their approval to have their individual
grades/scores posted via the downloadable Grade
Posting Permission Form. [click on the button below to
download this form]
Wtihout this form,
individual student scores/grades will not be posted. A student
may withdraw this permission at anytime by written notice to the course
instructor.
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NOTE: Each scheduled course day is broken
into two halves. The first half begins promptly
at 8:00 AM an last until approximately
9:00 AM. This session will always meet in the scheduled
classroom. The second half of each scheduled course day begins promptly at 9:15 AM (unless
otherwise noted or changed by Dr. Cooper) and ends at 10:15 AM.
Most of these sessions will meet on the fourth floor of Maag
Library. Dr. Cooper will provide additional instructions
regarding these second sessions.
Wednesday,
July 6th
1st Session: Course
Introduction
Introduction Memo (PDF)
Background
Reading: History of Medical Mycology in the United States.
ANA ESPINEL-INGROFF. CLINICAL
MICROBIOLOGY REVIEWS 9:
235–272, 1996. [PDF Document - Click HERE]
2nd Session: Library Orientation/Database
Search
Maag
Library, 4th Floor Instruction
Laboratory
Ms. Cynthia Harrison, Science
Librarian
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Friday,
July 8th
Syllabus
Acknowledgment Form Due
1st Session:
Lecture - What are Fungi?
Lecture
Slides (PDF)
Background
Reading: The Fifth Kingdom (on line) -
free digitial textbook on the fungal kingdom. This on line
version of the book contains almost all the material found int he
printed version. The introductory chapters address the question
"What are Fungi?"
2nd Session: Library
Research
Use this time to work as a group on
the research for your presentations.
During these sessions, Dr. Cooper
who will be in the
library on the 4th floor near the Tech Desk unitl about 10:15 AM.
Topic
|
Team
Members
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Candida and Candidiasis
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Adamson,
Bees,
Bischoff, and Candle
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Cryptococcus and Cryptococcosis
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Carlozzi,
Forte, and Galioto
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Malassezia Infections
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Gupta,
Lileas,
and Madden
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Aspergillosis
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Mohney,
Olenick, and Omair
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Zygomycosis
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Mariani,
Rose,
Runyon,
and Russell
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Dermatophyte
Infections
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Seman,
Speerstra, and Thurston
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Monday,
July 11h
1st
Session:
Lecture - What are Fungi? (cont.)
2nd Session: Library Research
(cont.)
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Tuesday,
July 12th
Last
Day to Add Classes or
Change
Grading Option
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Wednesday,
July 13th
1st Session:
Lecture - Epidemiology
of Fungal Infections
2nd Session: Library Research
(cont.)
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Friday,
July 15th
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Monday,
July 18th
Student Presentations II - Beginning at 8:30 AM
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Wednesday,
July 20th
1st Session:
Lecture - Fungal
Pathogenesis
2nd Session: Library Research
Topic
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Team Members
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Hyalohyphomycosis
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Candle,
Mohney, and Seman
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| Phaeohyphomycosis |
Carlozzi,
Madden, and Russell
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| Chromoblastomycois |
Forte,
Mariani, Runyon, and Thurston
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Histoplasmosis
|
Bischoff,
Lileas, and Rose
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| Blastomycosis |
Bees,
Gupta, Omair, and Speerstra
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| Coccidioidomycosis |
Adamson,
Galioto, and Olenick
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Friday,
July 22nd
1st Session:
Lecture - Immunology
of Fungal Infections
In Class
Assignment
2nd Session: Library Research
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Monday,
July 25th
1st Session: Exam
I
2nd Session: Library Research
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Wednesday,
July 27th
1st Session:
Lecture - Immunology
of Fungal Infections
(cont.)
2nd Session: Student Presentations III
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Thursday,
July 28th
Last Day for
Withdrawing with a Grade of 'W'
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Friday,
July 29th
1st Session:
Lecture - Histopathology
of
Fungal
Infections
2nd Session: Student Presentations IV
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Monday,
August 1st
1st Session: Lecture - Antifungal
Agents
2nd Session: Library Research
Topic
|
Team Members
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Penicillium marneffei Infections
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Bees,
Thurston, and
Speerstra
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| Sporotrichosis |
Galioto,
Lileas, Mariani, and Olenick
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| Paracoccidioidomycosis |
Adamson,
Carlozzi, and Runyon
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Lacaziosis
|
Bischoff,
Mohney, and Omair
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| Pythiosis |
Forte,
Gupta, and Rose
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| Rhinosporidiosis |
Madden,
Russell, and
Seman
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Wednesday,
August 3rd
NO CLASS MEETING
TODAY
Library
Research - ON YOUR OWN!!!!
You have your
assignments, so work in your groups. I will be available in my
office until 8:20 AM, then, if time permits, I will come by the 4th
floor of the library to answer questions
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Friday,
August 5th
1st Session:
Lecture - Antifungal
Agents (cont.)
2nd Session: Library Research |
Monday,
August 8th
1st Session: Videos: Specimen Collection and
Global Warming-Emerging Fungal Diseases
2nd Session: Student Presentations V
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Wednesday,
August 10th
NOTE: Class will begin at
8:30 AM
Student Presentations VI
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Friday,
August 12th
Exam
II
The exam will begin
promptly at 8:00 AM
Exam
results/final grades will be posted to this web page no later than
Sunday, August 14th.
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Multiple skin lesions due to disseminated infection
of Coccidioides immitis
(courtesy of www.doctorfungus.org)
Attendance:
A record of attendance
will be
kept
beginning on the second day of the course. Attendance is
worth 150 points towards a student's final grade. Each lecture
day, is worth 10 points (5 points per session). For a student to
receive a full day's attendance points, he/she must be present for the
entire period.
Please note, the lecture for this course
begins promptly at 8:00 AM throughout the
semester. Also, be aware that this course operates on "Ward
Beecher Time", which may
or may not
correlate to the time that exists at other places on campus.
Students are strongly encouraged to synchronize their
timepieces as well as to arrive early enough to find a suitable parking
place.
On those dates for which an examination is scheduled, students
who are late may not be permitted to take the examination. This
is
entirely at Dr. Cooper's discretion.
Moreover, except
for extenuating circumstances,
it is generally unacceptable for a student to request to take an
examination at a time other than the scheduled date. Having a
second
examination the day before, the day after, or on the same day is
absolutely certain not to evoke any sympathy from Dr. Cooper.
Please do not even ask for special dispensation for such a
reason.
However, Dr. Cooper is willing to listen (and perhaps chuckle to
himself) other reasons that a student may deem to be extenuating
(please note - havng in excess of two grandmothers die during the
semester will be considered suspicously gratuitous). The
decision
regarding the student's reasoned argument/request for a change in the
examination date/time is solely at Dr. Cooper's discretion and, once
rendered, is final.
Distribution
of
Course Material:
All original material on
the BIOL 4849 course web site, as well as all original material
presented in either the classroom or laboratory, including
orally-transmitted lectures, is considered protected by a copyright
held by Dr. Cooper. In general, students enrolled in BIOL
4849
have permission to download, print, and distribute materials
copyrighted by Dr. Cooper without his expressed written permission so
long as such materials are not used for activities i) associated with
the commission of academic dishonesty, ii) intended to circumvent
course policies, iii) which result in monetary profit by either the
student or others, and iv) that do not violate copyright
protections. For further information, please see Copyright
Restrictions.
Required
YSU Email Account:
All electronic
communications with students enrolled in BIOL 4849 will only be
made
using the University's myYSU email system. Students should
activate their myYSU accounts
if they have not done so already. To activate your free
myYSU account, go to the
web page located at the following URL: http://helpdesk.ysu.edu. Please note that a myYSU
account does not have to supplant your
current email service. A feature of the myYSU system is
that all
incoming messages can be forwarded to another email account.
Hence, you can retain your present services and still receive all
communications from Dr. Cooper.
Syllabus
Acknowledgement Form:
All
students enrolled in this course must read this electronic
syllabus and verify that they have done so by
submitting a completed Syllabus
Acknowledgement Form by July 7th.
[click on the button below to download this form]
No grades will be given
until this form is received.
Due by July 8th!!!
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